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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN14
All Species:
14.24
Human Site:
S526
Identified Species:
31.33
UniProt:
Q15678
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15678
NP_005392.2
1187
135261
S526
P
K
N
N
V
V
P
S
K
P
G
A
S
A
I
Chimpanzee
Pan troglodytes
XP_001171329
1187
135241
S526
P
K
N
N
V
V
P
S
K
P
G
A
S
T
I
Rhesus Macaque
Macaca mulatta
XP_001106167
1187
135194
S526
P
K
N
N
V
V
P
S
K
P
G
A
S
A
I
Dog
Lupus familis
XP_849236
1187
134903
S526
P
K
N
N
S
V
P
S
K
P
G
A
S
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q62130
1189
135012
I526
P
Q
N
C
A
M
P
I
K
P
G
A
S
S
I
Rat
Rattus norvegicus
Q62728
1175
133393
P532
P
Y
P
V
E
R
R
P
V
V
G
A
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511302
1193
135259
T531
N
H
T
V
Q
N
K
T
A
A
S
A
I
S
H
Chicken
Gallus gallus
XP_419419
1191
135566
K531
P
N
N
A
V
Q
N
K
T
A
A
S
A
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339962
834
94004
Y221
N
I
I
R
N
Q
V
Y
W
P
P
P
P
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
D413
S
A
A
R
H
D
T
D
S
S
D
A
L
G
Y
Sea Urchin
Strong. purpuratus
XP_796215
1318
147575
N537
Q
P
E
L
R
Q
H
N
H
N
N
H
Y
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
95.6
N.A.
91.5
53.7
N.A.
87.9
84.9
N.A.
32.8
N.A.
N.A.
N.A.
24.7
34.5
Protein Similarity:
100
99.7
99.5
97.2
N.A.
95.6
70.7
N.A.
92.1
91.5
N.A.
48.1
N.A.
N.A.
N.A.
42
51.7
P-Site Identity:
100
93.3
100
93.3
N.A.
60
20
N.A.
6.6
20
N.A.
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
80
33.3
N.A.
20
33.3
N.A.
6.6
N.A.
N.A.
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
10
0
0
0
10
19
10
73
10
28
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
55
0
0
10
0
% G
% His:
0
10
0
0
10
0
10
0
10
0
0
10
0
0
10
% H
% Ile:
0
10
10
0
0
0
0
10
0
0
0
0
10
10
46
% I
% Lys:
0
37
0
0
0
0
10
10
46
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
10
55
37
10
10
10
10
0
10
10
0
0
0
0
% N
% Pro:
64
10
10
0
0
0
46
10
0
55
10
10
10
0
10
% P
% Gln:
10
10
0
0
10
28
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
19
10
10
10
0
0
0
0
0
0
10
0
% R
% Ser:
10
0
0
0
10
0
0
37
10
10
10
10
46
28
10
% S
% Thr:
0
0
10
0
0
0
10
10
10
0
0
0
0
10
0
% T
% Val:
0
0
0
19
37
37
10
0
10
10
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
10
0
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _